{"id":1776,"date":"2009-10-22T07:14:42","date_gmt":"2009-10-22T11:14:42","guid":{"rendered":"http:\/\/asweetlife.org\/?p=1776"},"modified":"2015-12-28T05:29:55","modified_gmt":"2015-12-28T10:29:55","slug":"isis-pharmaceuticals-positive-phase-2-data-for-isis-113715","status":"publish","type":"post","link":"https:\/\/asweetlife.org\/?p=1776","title":{"rendered":"Isis Pharmaceuticals: Positive Phase 2 Data for ISIS 113715"},"content":{"rendered":"<p style=\"text-align: justify;\"><a href=\"https:\/\/asweetlife.org\/wp-content\/uploads\/2009\/10\/Isis-Pharmaceuticals-logo-1.png\" rel=\"mfp\"><img decoding=\"async\" class=\"alignleft size-full wp-image-29500 lazyload\" title=\"Isis Pharmaceuticals logo\" src=\"data:image\/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==\" data-src=\"https:\/\/asweetlife.org\/wp-content\/uploads\/2009\/10\/Isis-Pharmaceuticals-logo-1.png\" alt=\"\" width=\"185\" height=\"59\" \/><\/a>Isis pharmaceuticals announced positive mid-stage trial results for the drug called ISIS 113715.\u00a0 The drug, tested on Type 2 diabetics with poor glucose control, not only lowered blood glucose, but also caused reductions in LDL cholesterol and a tendency towards weight loss. \u00a0<span>Robert Henry, M.D., Professor of Medicine, University of California at San Diego and Chief, Section of Diabetes, Endocrinology and Metabolism at VA San Diego said, <\/span><span>&#8220;If the profile of ISIS 113715 seen in this study is confirmed in longer-term trials, the drug could be an important addition to the care of type 2 diabetic patients.&#8221;<\/span><\/p>\n<p style=\"text-align: justify;\"><span>ISIS 113715 is a novel insulin sensitizer that reduces the expression of the protein tyrosine phosphate (PTP-1B).\u00a0 The drug was well tolerated by patients, with the most common side-effect being mild injection site reactions.<br \/> <\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Isis pharmaceuticals announced positive mid-stage trial results for the drug called ISIS 113715.  The drug, tested on Type 2 diabetics with poor glucose control, not only lowered blood glucose, but also caused reductions in LDL cholesterol and a tendency towards weight loss.  Robert Henry, M.D., Professor of Medicine, University of California at San Diego and Chief, Section of Diabetes, <\/p>\n","protected":false},"author":131,"featured_media":29500,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_relevanssi_hide_post":"","_relevanssi_hide_content":"","_relevanssi_pin_for_all":"","_relevanssi_pin_keywords":"","_relevanssi_unpin_keywords":"","_relevanssi_related_keywords":"","_relevanssi_related_include_ids":"","_relevanssi_related_exclude_ids":"","_relevanssi_related_no_append":"","_relevanssi_related_not_related":"","_relevanssi_related_posts":"","_relevanssi_noindex_reason":"","footnotes":""},"categories":[1443],"tags":[222],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v22.9 (Yoast SEO v22.9) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Isis Pharmaceuticals: Positive Phase 2 Data for New Type 2 Diabetes Drug<\/title>\n<meta name=\"description\" content=\"Isis pharmaceuticals announced positive mid-stage trial results for the drug called ISIS 113715. The drug, tested on Type 2 diabetics with poor glucose control...\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/asweetlife.org\/?p=1776\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"ASweetLife Team\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/asweetlife.org\/?p=1776\",\"url\":\"https:\/\/asweetlife.org\/?p=1776\",\"name\":\"Isis Pharmaceuticals: Positive Phase 2 Data for New Type 2 Diabetes Drug\",\"isPartOf\":{\"@id\":\"https:\/\/asweetlife.org\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/asweetlife.org\/?p=1776#primaryimage\"},\"image\":{\"@id\":\"https:\/\/asweetlife.org\/?p=1776#primaryimage\"},\"thumbnailUrl\":\"https:\/\/asweetlife.org\/wp-content\/uploads\/2009\/10\/Isis-Pharmaceuticals-logo-1.png\",\"datePublished\":\"2009-10-22T11:14:42+00:00\",\"dateModified\":\"2015-12-28T10:29:55+00:00\",\"author\":{\"@id\":\"https:\/\/asweetlife.org\/#\/schema\/person\/5de2b093878b82b0ea97917f8fd72585\"},\"description\":\"Isis pharmaceuticals announced positive mid-stage trial results for the drug called ISIS 113715. 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