{"id":19286,"date":"2011-08-29T11:30:06","date_gmt":"2011-08-29T15:30:06","guid":{"rendered":"http:\/\/asweetlife.org\/?p=19286"},"modified":"2015-12-27T15:48:29","modified_gmt":"2015-12-27T20:48:29","slug":"diapep277-and-me","status":"publish","type":"post","link":"https:\/\/asweetlife.org\/?p=19286","title":{"rendered":"Diapep277 and Me"},"content":{"rendered":"

\"\"<\/a>When I was first diagnosed with type 1 diabetes, I was asked to participate in a clinical study for a diabetes “vaccine” called Diapep277.\u00a0 I didn\u2019t know anything about it (nor did I know anything about diabetes).\u00a0 At the time, what convinced me to enter the study was not a belief that my diabetes would disappear, but the fact that I’d have a team of endocrinologists looking after me closely for a year.\u00a0 After losing twenty pounds, having my vision go blurry, and losing feeling in my toes, nothing was more appealing than a year of good doctors taking care of me.<\/p>\n

The doctors administering the trial explained to me that although what I was getting could not cure me it could slow down the process of beta cell destruction or maybe even halt it (if I was actually getting the real thing).\u00a0 Like many newly diagnosed type 1\u2019s, I was enjoying a honeymoon period and injecting very little insulin.<\/p>\n

For the first few months of the experiment I went to the hospital once every other week, received an injection of some sort (I didn\u2019t know if it was Diapep277 or the placebo) and then had glucagon injected into my vein. After that, the doctor took blood from my arm every few minutes for a while. I don\u2019t remember if it was an hour or two, but they took a large number of vials.<\/p>\n

\"Diapep277<\/a>
How Diapep277 Works<\/figcaption><\/figure>\n

In a way, I enjoyed my hospital days, which my bosses at the time where very understanding about. It was a half day off of work and a break from my usual routine.\u00a0 Plus, when I met with the other study participants it was a chance (in the days before the DOC) to meet other people with diabetes.\u00a0 However, let me say a word or two about the glucagon injection. \u00a0Horrible nausea! I literally spent three minutes wishing I were dead every time I got it.<\/p>\n

After the first two or three months of the study, the hospital visits became less frequent until I was told the trial was over. \u00a0Although when I’d started I was told I’d be informed at the trial’s end whether I’d received the drug or the placebo, I never heard anything.\u00a0 A few years later, I asked someone working in the diabetes clinic at hospital about it and was told that I had received the real thing and not the placebo.\u00a0 I don’t, however, have that in writing.\u00a0 If I did in fact get the drug, I don’t know which dose I received.<\/p>\n

Sometime around the end of my first year as a diabetic my honeymoon period ended. It didn\u2019t happen all at once, but with time I was injecting 30-50 units a day depending on the diet I followed.\u00a0 Because of this I always assumed the trial was not successful, and that it didn\u2019t do me any good.<\/p>\n

A couple months ago, after I read Karmel Allison\u2019s blog<\/a> post about C-peptide and diabetes complications, I decided to ask my doctor to include a C-peptide test on my last blood work.\u00a0 If I still had some C-peptide, perhaps it would be sign that Diapep277 had been good to me. \u00a0It took over a week for the results to come in, but it was worth the wait.<\/p>\n

\"\"<\/a>Although it doesn\u2019t seem like it (especially after my last race<\/a>), my body still produces some insulin. My C-peptide is 111. <\/strong>This is of course <\/strong>way out of the normal <\/strong>range which is 298 to 2350 (according to my lab), but it is still far from zero.<\/p>\n

I’m in the process of trying to find out for certain if I received the drug, and if so at which dose.\u00a0 And then it will be easier to guess whether the Phase II Diapep 277 trial has anything to do with it my current C-peptide level.<\/p>\n

*Images are taken from the AndromedA Biotech<\/a> web site.<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"

…<\/p>\n","protected":false},"author":129,"featured_media":53098,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_relevanssi_hide_post":"","_relevanssi_hide_content":"","_relevanssi_pin_for_all":"","_relevanssi_pin_keywords":"","_relevanssi_unpin_keywords":"","_relevanssi_related_keywords":"","_relevanssi_related_include_ids":"","_relevanssi_related_exclude_ids":"","_relevanssi_related_no_append":"","_relevanssi_related_not_related":"","_relevanssi_related_posts":"","_relevanssi_noindex_reason":"","footnotes":""},"categories":[1501],"tags":[930],"yoast_head":"\nDiapep277 and Me<\/title>\n<meta name=\"description\" content=\"When I was first diagnosed with type 1 diabetes, I was asked to participate in a clinical study for a diabetes "vaccine" called Diapep277...\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" 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