{"id":21042,"date":"2011-10-24T10:40:38","date_gmt":"2011-10-24T14:40:38","guid":{"rendered":"http:\/\/asweetlife.org\/?p=21042"},"modified":"2016-01-06T06:28:34","modified_gmt":"2016-01-06T11:28:34","slug":"the-loop-has-closed-the-artificial-pancreas-program-comes-to-life-in-israel","status":"publish","type":"post","link":"https:\/\/asweetlife.org\/?p=21042","title":{"rendered":"The Loop Has Closed: The Artificial Pancreas Program Comes to Life in Israel"},"content":{"rendered":"<p>&nbsp;<\/p>\n<p style=\"text-align: justify;\">Diabetes technology has vastly improved in the last decade, and most people with diabetes who have the opportunity to wear an insulin pump or a continuous glucose monitor are grateful for the assistance they provide.\u00a0 But even with these advanced tools, the biggest burdens of diabetes &#8211; the insulin dosing and blood sugar testing &#8211; still lie on the person with diabetes or a caregiver.<\/p>\n<p style=\"text-align: justify;\">Just about every adult with diabetes\u00a0 will tell you how much they&#8217;d like to eat without thinking about each and every bite.\u00a0 Every parent of a child with diabetes wants their child to be able to eat without having to calculate and dose insulin for them.\u00a0 And most of all, people with diabetes and their caregivers would like to sleep without the fear of hypoglycemia.\u00a0 Thanks to the work of <a href=\"http:\/\/www.schneider.org.il\/Eng\/Index.asp?CategoryID=65&amp;ArticleID=231\" target=\"_blank\">Professor Moshe Phillip<\/a> and his team at the <a href=\"http:\/\/www.schneider.org.il\/Eng\/Index.asp?CategoryID=37&amp;ArticleID=26\" target=\"_blank\">Institute of Endocrinology and Diabetes at Schneider Children\u2019s Medical Center <\/a>of Israel and Eran Atlas, head of the engineering team at the Diabetes Technology Institute at Schneider Children\u2019s, we&#8217;re one step closer to carefree eating and peaceful nights.\u00a0 We&#8217;re one step closer to being relieved of the continuous need to check blood glucose levels, calculate insulin requirements, and inject insulin.<\/p>\n<p style=\"text-align: justify;\">Earlier this month, Prof. Phillip and his team invited 18 children with diabetes in Israel to be part of the world&#8217;s first out-of-hospital artificial pancreas trial.\u00a0 The trial took place on Kibbutz Ma&#8217;ale Hahamisha in the hills outside of Jerusalem, and utilized the MD-Logic system developed at Schneider Children\u2019s.\u00a0 The MD-Logic system allows real-time control of the blood glucose levels based on readings from a continuous glucose sensor. It is based on a model which imitates the logic of diabetes caregivers.*<\/p>\n<h2>How did the Artificial Pancreas Program work?<\/h2>\n<p style=\"text-align: justify;\">1. 18 children between the ages of 12-15 years were invited to participate.<\/p>\n<p style=\"text-align: justify;\">2. The children gathered to meet each other, play getting-to-know-each-other games, and talk about how many years they&#8217;d been living with diabetes.<\/p>\n<p style=\"text-align: justify;\">3. Nine children were connected to the program\u2019s network.\u00a0 (The other nine children were connected to the network a day later.)<\/p>\n<p style=\"text-align: justify;\">4.\u00a0 Each child was connected to an insulin pump, a continuous glucose sensor, and an artificial pancreas in the form of a laptop computer which communicated between the pump and the glucose sensor.\u00a0 The artificial pancreas determined how many units of insulin to deliver, was responsible for suspending insulin delivery in case of low blood sugar, and made adjustments in basal rates.\u00a0 All of this was done without any human input.<\/p>\n<p style=\"text-align: justify;\">5. Each child wore\/carried a backpack which held the laptop computer\/artificial pancreas.\u00a0 When the child slept, the computer sat on a small table beside the bed.<\/p>\n<p style=\"text-align: justify;\">6. Throughout the experiment, including the nighttime hours, the doctors and engineers who developed the Artificial Pancreas Program sat in a control room where they observed and monitored all of the data for all of the children.\u00a0 If a problem arose, they were able to detect it and correct it immediately.<\/p>\n<p style=\"text-align: justify;\">The trial was considered successful, and though there is still some way to go before the artificial pancreas becomes standard diabetes care, it&#8217;s an exciting and promising step.\u00a0 It&#8217;s kind of like giving diabetes a brain, which is a wonderful thing for those of us who feel like our diabetes has a mind of its own.<\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: x-small;\">*Closing the Loop \u2013 Towards an Artificial Pancreas \u2013 The Schneider Medical Center Experience<\/span><br \/>\n<span style=\"font-size: x-small;\">Revital Nimri, Eran Atlas, Shahar Miller, Eli Grunberg, Moshe Phillip, http:\/\/www.ies.org.il\/abstracts09\/Stem%20cell%20in%20Diabetes%20Mellitus%20symposia-HW103-106.pdf<\/span><\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Diabetes technology has vastly improved in the last decade, and most people with diabetes who have the opportunity to wear an insulin pump or a continuous glucose monitor are grateful for the assistance they provide.  But even with these advanced tools, the biggest burdens of diabetes &#8211; the insulin dosing and blood sugar testing &#8211; still lie on the person with diabetes or a caregiver. <\/p>\n","protected":false},"author":8,"featured_media":41561,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"image","meta":{"_relevanssi_hide_post":"","_relevanssi_hide_content":"","_relevanssi_pin_for_all":"","_relevanssi_pin_keywords":"","_relevanssi_unpin_keywords":"","_relevanssi_related_keywords":"","_relevanssi_related_include_ids":"","_relevanssi_related_exclude_ids":"","_relevanssi_related_no_append":"","_relevanssi_related_not_related":"","_relevanssi_related_posts":"","_relevanssi_noindex_reason":"","footnotes":""},"categories":[1448,1430],"tags":[415,20],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v22.9 (Yoast SEO v22.9) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>The Artificial Pancreas Program Comes to Life in Israel<\/title>\n<meta name=\"description\" content=\"In Israel, 18 children with diabetes were part of the world&#039;s first out-of-hospital artificial pancreas trial...\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/asweetlife.org\/?p=21042\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Jessica Apple\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"3 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/asweetlife.org\/?p=21042\",\"url\":\"https:\/\/asweetlife.org\/?p=21042\",\"name\":\"The Artificial Pancreas Program Comes to Life in Israel\",\"isPartOf\":{\"@id\":\"https:\/\/asweetlife.org\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/asweetlife.org\/?p=21042#primaryimage\"},\"image\":{\"@id\":\"https:\/\/asweetlife.org\/?p=21042#primaryimage\"},\"thumbnailUrl\":\"https:\/\/asweetlife.org\/wp-content\/uploads\/2011\/10\/TomwithBackpack-1.jpg\",\"datePublished\":\"2011-10-24T14:40:38+00:00\",\"dateModified\":\"2016-01-06T11:28:34+00:00\",\"author\":{\"@id\":\"https:\/\/asweetlife.org\/#\/schema\/person\/1f33fe649de04a31a493d746b6e72607\"},\"description\":\"In Israel, 18 children with diabetes were part of the world's first out-of-hospital artificial pancreas trial...\",\"breadcrumb\":{\"@id\":\"https:\/\/asweetlife.org\/?p=21042#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/asweetlife.org\/?p=21042\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/asweetlife.org\/?p=21042#primaryimage\",\"url\":\"https:\/\/asweetlife.org\/wp-content\/uploads\/2011\/10\/TomwithBackpack-1.jpg\",\"contentUrl\":\"https:\/\/asweetlife.org\/wp-content\/uploads\/2011\/10\/TomwithBackpack-1.jpg\",\"width\":600,\"height\":348,\"caption\":\"The Artificial Pancreas Program Comes to Life in Israel\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/asweetlife.org\/?p=21042#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/asweetlife.org\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"The Loop Has Closed: The Artificial Pancreas Program Comes to Life in Israel\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/asweetlife.org\/#website\",\"url\":\"https:\/\/asweetlife.org\/\",\"name\":\"ASweetLife\",\"description\":\"The Diabetes Magazine\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/asweetlife.org\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\/\/asweetlife.org\/#\/schema\/person\/1f33fe649de04a31a493d746b6e72607\",\"name\":\"Jessica Apple\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/asweetlife.org\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/c10409e04c60ee9e1a01fbe9c4a704b9?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/c10409e04c60ee9e1a01fbe9c4a704b9?s=96&d=mm&r=g\",\"caption\":\"Jessica Apple\"},\"description\":\"Jessica Apple grew up in Houston. 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