{"id":22751,"date":"2011-12-07T06:38:10","date_gmt":"2011-12-07T11:38:10","guid":{"rendered":"http:\/\/asweetlife.org\/?p=22751"},"modified":"2015-12-29T08:53:10","modified_gmt":"2015-12-29T13:53:10","slug":"new-studies-show-novo-nordisks-combination-insulin-reduces-hypoglycemia","status":"publish","type":"post","link":"https:\/\/asweetlife.org\/?p=22751","title":{"rendered":"New Studies Show Novo Nordisk’s Combination Insulin Reduces Hypoglycemia"},"content":{"rendered":"

\"\"<\/a>A study\u00a0released by Novo Nordisk at the International Diabetes Federation (IDF) 21st World Diabetes Congress in Dubai has found that\u00a0the combination insulin degludec<\/a>\/insulin aspart, currently being developed,\u00a0significantly reduced hypoglycemia in type 1 diabetes and type 2 diabetes patients.\u00a0<\/p>\n

In the study, insulin degludec\/insulin aspart reduced the overall occurrence of hypoglycemia during the day as well as at night (occurring between 23:00 and 05:59). The study found that type 2 diabetes patients using Insulin degludec\/insulin aspart reduced rates of hypoglycemia by 58% compared to biphasic insulin aspart when dosed twice-daily.<\/p>\n
Improvements in fasting plasma glucose (FPG) were also seen, with levels significantly lower in the insulin degludec\/insulin aspart group vs \u00a0biphasic insulin aspart (6.4 vs. 7.5 mmol\/l). The study also found that insulin degludec\/insulin aspart was well tolerated and provided comparable overall glycemic control to biphasic insulin aspart.<\/div>\n
\u00a0<\/div>\n
A second study also presented showed that rates of hypoglycemia at night were reduced by 37% in people with type 1 diabetes using once-daily insulin degludec\/insulin aspart (with additional rapid-acting mealtime insulin doses for the remaining meals), compared to those using once-daily insulin detemir plus rapid-acting insulin at all main meals.<\/div>\n
\u00a0<\/div>\n
Insulin degludec\/insulin aspart, in development by Novo Nordisk, will, pending approval, be the only soluble insulin combination of ultra-long-acting basal insulin degludec and rapid-acting insulin, insulin aspart. Clinical studies have shown that it provides fasting plasma glucose control with significantly less hypoglycemia compared to premix insulin.\u00a0<\/div>\n
\n
\"\"<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

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