{"id":25696,"date":"2012-03-20T05:26:06","date_gmt":"2012-03-20T09:26:06","guid":{"rendered":"http:\/\/asweetlife.org\/?p=25696"},"modified":"2015-12-28T09:01:19","modified_gmt":"2015-12-28T14:01:19","slug":"experimental-diabetes-drug-shows-improved-glycemic-control","status":"publish","type":"post","link":"https:\/\/asweetlife.org\/?p=25696","title":{"rendered":"Experimental Diabetes Drug Shows Improved Glycemic Control"},"content":{"rendered":"<div>\n<div style=\"text-align: justify;\"><span style=\"font-family: arial, helvetica, sans-serif;\"><a href=\"https:\/\/asweetlife.org\/wp-content\/uploads\/2012\/03\/Bristol-Myers-Logo-1.png\" rel=\"mfp\"><img decoding=\"async\" class=\"alignleft size-full wp-image-25698 lazyload\" title=\"Bristol-Myers Logo\" src=\"data:image\/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==\" data-src=\"https:\/\/asweetlife.org\/wp-content\/uploads\/2012\/03\/Bristol-Myers-Logo-1.png\" alt=\"\" width=\"158\" height=\"128\" \/><\/a>A new study evaluating the efficacy and safety of adding dapagliflozin therapy\u00a0to the treatment of type 2 diabetes\u00a0patients whose blood glucose levels remain\u00a0poorly controlled despite high doses of insulin\u00a0was published today in the\u00a0<\/span><em style=\"font-family: arial, helvetica, sans-serif;\">Annuls of Internal Medicine<\/em><span style=\"font-family: arial, helvetica, sans-serif;\">.<\/span><\/div>\n<\/div>\n<div style=\"text-align: justify;\">\n<div><span style=\"font-family: arial, helvetica, sans-serif;\"><br \/><\/span><\/div>\n<\/div>\n<div style=\"text-align: justify;\"><span style=\"font-family: arial, helvetica, sans-serif;\">The 24 week study conducted on\u00a0808 type 2 diabetes patients\u00a0with inadequately controlled blood sugar despite receiving insulin with or without pills by mouth\u00a0found that patients who received dapagliflozin had better control of blood sugar and had more weight loss than patients who received placebo. The patients who received dapagliflozin were also receiving lower doses of insulin at the end of the trial than those who received placebo. However, more episodes of low blood sugar occurred in patients receiving dapagliflozin than those receiving placebo. In addition, dapagliflozin causes sugar to accumulate in the urine, which raises concern that it might increase genital infections. An increase in genital infections was reported in the patients who received dapagliflozin, although these infections responded to antibiotic treatment.<\/span><\/div>\n<div style=\"text-align: justify;\"><span style=\"font-family: arial, helvetica, sans-serif;\"><br \/><\/span><\/div>\n<div style=\"text-align: justify;\"><span style=\"font-family: arial, helvetica, sans-serif;\"><span style=\"font-family: arial, helvetica, sans-serif;\">The researchers concluded that\u00a0Dapagliflozin improves glycemic control, stabilizes insulin dosing, and reduces weight without increasing major hypoglycemic episodes in patients with inadequately controlled type 2 diabetes.<\/span><\/span><\/p>\n<p><em><span style=\"font-family: arial, helvetica, sans-serif;\">Dapagliflozin\u00a0is<strong>\u00a0<\/strong>an experimental drug being studied by\u00a0Bristol-Myers Squibb\u00a0in partnership with\u00a0AstraZeneca\u00a0as a potential treatment for\u00a0type 1\u00a0and\u00a02 diabetes. Although dapagliflozin&#8217;s method of action would operate on either type of diabetes or other conditions resulting in\u00a0hyperglycemia, the current clinical trials are being conducted only on patients with type 2 diabetes.<\/span><\/em><\/p>\n<\/div>\n<div style=\"text-align: justify;\">\u00a0<\/div>\n<div style=\"text-align: justify;\">\u00a0<\/div>\n<div style=\"text-align: justify;\">\u00a0<\/div>\n","protected":false},"excerpt":{"rendered":"<p>A new study evaluating the efficacy and safety of adding dapagliflozin therapy to the treatment of type 2 diabetes patients whose blood glucose levels remain poorly controlled despite high doses of insulin was published today in the Annuls of Internal Medicine&#8230;<\/p>\n","protected":false},"author":131,"featured_media":25698,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_relevanssi_hide_post":"","_relevanssi_hide_content":"","_relevanssi_pin_for_all":"","_relevanssi_pin_keywords":"","_relevanssi_unpin_keywords":"","_relevanssi_related_keywords":"","_relevanssi_related_include_ids":"","_relevanssi_related_exclude_ids":"","_relevanssi_related_no_append":"","_relevanssi_related_not_related":"","_relevanssi_related_posts":"","_relevanssi_noindex_reason":"","footnotes":""},"categories":[1442],"tags":[684,683,1332],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v22.9 (Yoast SEO v22.9) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Experimental Diabetes Drug Shows Improved Glycemic Control<\/title>\n<meta name=\"description\" content=\"A new study evaluating the efficacy and safety of adding dapagliflozin therapy to the treatment of 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