{"id":27468,"date":"2012-05-22T09:35:54","date_gmt":"2012-05-22T13:35:54","guid":{"rendered":"http:\/\/asweetlife.org\/?p=27468"},"modified":"2015-12-30T04:42:30","modified_gmt":"2015-12-30T09:42:30","slug":"novo-nordisks-levemir-insulin-approved-for-use-in-children-as-young-as-two","status":"publish","type":"post","link":"https:\/\/asweetlife.org\/?p=27468","title":{"rendered":"Novo Nordisk&#8217;s Levemir Insulin Approved for Use in Children as Young as Two"},"content":{"rendered":"<p style=\"text-align: justify;\"><a href=\"https:\/\/asweetlife.org\/wp-content\/uploads\/2012\/05\/Levemir.jpg\" rel=\"mfp\"><img decoding=\"async\" class=\"alignleft size-full wp-image-27469 lazyload\" title=\"Levemir\" src=\"data:image\/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==\" data-src=\"https:\/\/asweetlife.org\/wp-content\/uploads\/2012\/05\/Levemir.jpg\" alt=\"\" width=\"250\" height=\"125\" \/><\/a>The\u00a0U.S. Food and Drug Administration (FDA) has approved Levemir\u00a0(insulin detemir [rDNA origin] injection) for use in children ages two to five years with type 1 diabetes, making it\u00a0the first and only basal insulin analog for use in this young patient group.\u00a0With the expansion of its pediatric indication, Levemir\u00a0is now available for type 1 diabetes patients from age two through adulthood and adult patients with type 2 diabetes, as well as <a href=\"https:\/\/asweetlife.org\/a-sweet-life-staff\/featured\/using-insulin-in-pregnancy-fda-approves-levemir\/26310\/\">pregnant patients<\/a>.<\/p>\n<p style=\"text-align: justify;\">The FDA decision was based on data that showed that Levemir\u00a0is an equally efficacious treatment option for two- to five-year-old children with type 1 diabetes, compared with Neutral Protamine Hagedorn (NPH) insulin. Mean HbA1c was similar between groups.<sup>\u00a0<\/sup>According to 2012 American Diabetes Association guidelines, it is recommended that children younger than age six have an A1c goal of less than 8.5 percent.\u00a0<\/p>\n<p style=\"text-align: justify;\">Each year, more than 13,000 young people are diagnosed with type 1 diabetes.\u00a0The youngest of these children with type 1 diabetes have the greatest likelihood of severe hypoglycemia and the highest risk of acute diabetes complications.\u00a0<\/p>\n<p style=\"text-align: justify;\">This pre-specified and stratified subgroup data showed that children with type 1 diabetes from ages two to five who received Levemir\u00a0plus a\u00a0rapid acting\u00a0insulin analog, NovoLog\u00a0(insulin aspart [rDNA origin] injection), experienced a low rate of hypoglycemia compared with those taking NPH and NovoLog\u00a0(24-hour: 50.6 vs. 78.3 episodes per patient year).<sup>\u00a0<\/sup>No patients treated with Levemir\u00a0had a severe hypoglycemic episode, whereas there were six reported episodes in three patients treated with NPH.<\/p>\n<p style=\"text-align: justify;\">In September 2011, the European Committee for Medicinal Products for Human Use (CHMP) similarly adopted a positive opinion on the extended use of Levemir\u00a0in children ages two to five years with type 1 diabetes.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The U.S. Food and Drug Administration (FDA) has approved Levemir (insulin detemir [rDNA origin] injection) for use in children ages two to five years with type 1 diabetes, making it the first and only basal insulin analog for use in this young patient group. With the expansion of its pediatric indication&#8230;<\/p>\n","protected":false},"author":131,"featured_media":27469,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_relevanssi_hide_post":"","_relevanssi_hide_content":"","_relevanssi_pin_for_all":"","_relevanssi_pin_keywords":"","_relevanssi_unpin_keywords":"","_relevanssi_related_keywords":"","_relevanssi_related_include_ids":"","_relevanssi_related_exclude_ids":"","_relevanssi_related_no_append":"","_relevanssi_related_not_related":"","_relevanssi_related_posts":"","_relevanssi_noindex_reason":"","footnotes":""},"categories":[1441],"tags":[144],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v22.9 (Yoast SEO v22.9) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Novo Nordisk&#039;s Levemir Insulin Approved for Use in Children as Young as Two<\/title>\n<meta name=\"description\" content=\"The U.S. FDA has approved Levemir (insulin detemir 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