{"id":29864,"date":"2012-07-26T07:13:55","date_gmt":"2012-07-26T11:13:55","guid":{"rendered":"http:\/\/asweetlife.org\/?p=28608"},"modified":"2015-12-30T03:26:45","modified_gmt":"2015-12-30T08:26:45","slug":"nih-awards-biodel-grant-to-develop-ultra-rapid-acting-insulin-for-use-in-artificial-pancreas","status":"publish","type":"post","link":"https:\/\/asweetlife.org\/?p=29864","title":{"rendered":"NIH Awards Biodel Grant to Develop Ultra-Rapid-Acting Insulin for Use in Artificial Pancreas"},"content":{"rendered":"
\"\"<\/a>The\u00a0Small Business Innovation Research\u00a0(SBIR) program of the\u00a0National Institutes of Health\u00a0(NIH) has awarded\u00a0Biodel\u00a0a grant for the development of concentrated ultra-rapid-acting insulin formulations for use in an artificial pancreas, also known as a closed loop pump system.<\/div>\n

The two-year, $582,473 grant, is intended to fund research to develop\u00a0Biodel’s proprietary ultra-rapid-acting insulin product candidate at high concentrations suited to provide sufficient quantities of insulin in an external artificial pancreas pump device that has a limited volume capacity.<\/p>\n

Currently, regular insulin at concentrations of 500 units per milliliter is used to treat extremely insulin resistant patients with diabetes. While these formulations are 5-times more concentrated than typical insulin presentations, they have a prolonged duration of action that may be undesirable for use with an artificial pancreas.<\/p>\n

Concentrated formulations of\u00a0Biodel’s ultra-rapid-acting insulin may be absorbed more rapidly than existing concentrated insulin formulations and may therefore become an important component of an effective step in the development of an artificial pancreas.<\/p>\n

\u00a0<\/div>\n","protected":false},"excerpt":{"rendered":"

The Small Business Innovation Research (SBIR) program of the National Institutes of Health (NIH) has awarded Biodel a grant for the development of concentrated ultra-rapid-acting insulin formulations for use in an artificial pancreas, also known as a closed loop pump system.<\/p>\n","protected":false},"author":131,"featured_media":29946,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_relevanssi_hide_post":"","_relevanssi_hide_content":"","_relevanssi_pin_for_all":"","_relevanssi_pin_keywords":"","_relevanssi_unpin_keywords":"","_relevanssi_related_keywords":"","_relevanssi_related_include_ids":"","_relevanssi_related_exclude_ids":"","_relevanssi_related_no_append":"","_relevanssi_related_not_related":"","_relevanssi_related_posts":"","_relevanssi_noindex_reason":"","footnotes":""},"categories":[1441],"tags":[488,862],"yoast_head":"\nNIH Awards Biodel Grant to Develop Ultra-Rapid-Acting Insulin for Use in Artificial 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