{"id":31885,"date":"2013-01-30T05:56:51","date_gmt":"2013-01-30T10:56:51","guid":{"rendered":"http:\/\/asweetlife.org\/?post_type=news&p=31885"},"modified":"2015-12-30T03:02:07","modified_gmt":"2015-12-30T08:02:07","slug":"diamyd-to-launch-new-clinical-study-of-diabetes-vaccine-in-children","status":"publish","type":"post","link":"https:\/\/asweetlife.org\/?p=31885","title":{"rendered":"Diamyd to Launch New Clinical Study of Diabetes Vaccine in Children"},"content":{"rendered":"

\"\"<\/a>Diamyd Medical is planning to launch a new clinical study with its diabetes vaccine, Diamyd, during February\u00a02013.<\/span><\/p>\n

\n

The study,\u00a0approved by the Swedish Medical Products Agency, combines the diabetes vaccine Diamyd\u00a0with relatively high doses of vitamin D and the anti-inflammatory drug ibuprofen. The purpose of the treatment is to preserve the body’s own ability to control the blood sugar level in children and adolescents newly diagnosed with type 1 diabetes.<\/p>\n

The study is called DIABGAD-1 and will also evaluate the effect of a double dose of Diamyd\u00a0and the protein GAD, which is the active substance in Diamyd. The study will include 60 children and adolescents in Sweden and it will be conducted at pediatric diabetes clinics in Malm\u00f6, Lund, Halmstad, Kalmar, J\u00f6nk\u00f6ping, Uddevalla, \u00d6rebro, Link\u00f6ping and Stockholm. The study is funded by research grants, while Diamyd Medical is responsible for providing study drug and certain other costs, and can utilize the study results.<\/p>\n

DIABGAD-1 is a double-blind, randomized and placebo-controlled Phase II study including a total of 60 participants between 10 and 18 years old, newly diagnosed with type 1 diabetes. The study will comprise a total of 30 months, with a first analysis focusing on immunological markers already after 6 months. The study has been approved by the Swedish Medical Products Agency and is scheduled to start screening patients in the beginning of February\u00a02013. Four different treatment groups, each including 15 participants, will be evaluated: the first group will receive one prime injection of Diamyd\u00a0and a booster injection 4 weeks later, combined with ibuprofen for 90 days and vitamin D for 450 days; the second group will receive one prime injection of Diamyd\u00a0and a booster injection 4 weeks later, and vitamin D for 450 days; the third group will receive two prime injections of Diamyd\u00a0and two booster injections 4 weeks later, and vitamin D for 450 days; and the fourth group will receive placebo only.<\/p>\n

Diamyd Medical\u2019s drug development in diabetes originates from the protein GAD, which is the active substance in the company\u2019s diabetes vaccine Diamyd\u00a0for the prevention and treatment of autoimmune diabetes. Treatment with Diamyd\u00a0is intended to prevent, delay, or stop the autoimmune attack on the beta cells. The aim is to prevent the onset of autoimmune diabetes, or to preserve the body\u2019s capacity to regulate blood sugar. Studies have shown that even a very small preservation of endogenous insulin secretion and slight improvement of the blood sugar control can significantly reduce the risk of both acute and long-term diabetes complications.<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

Diamyd Medical is planning to launch a new clinical study with its diabetes vaccine, Diamyd, during February 2013.
\nThe study, approved by the Swedish Medical Products Agency, combines the diabetes vaccine Diamyd with relatively high doses of vitamin D and the anti-inflammatory drug ibuprofen. The purpose of the treatment is to preserve the body’s own ability to control the blood sugar level in children and adolescents newly diagnosed with type 1 diabetes.<\/p>\n","protected":false},"author":131,"featured_media":31886,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_relevanssi_hide_post":"","_relevanssi_hide_content":"","_relevanssi_pin_for_all":"","_relevanssi_pin_keywords":"","_relevanssi_unpin_keywords":"","_relevanssi_related_keywords":"","_relevanssi_related_include_ids":"","_relevanssi_related_exclude_ids":"","_relevanssi_related_no_append":"","_relevanssi_related_not_related":"","_relevanssi_related_posts":"","_relevanssi_noindex_reason":"","footnotes":""},"categories":[1446,1445],"tags":[535],"yoast_head":"\nDiamyd to Launch New Clinical Study of Diabetes Vaccine in Children<\/title>\n<meta name=\"description\" content=\"The study combines the diabetes vaccine Diamyd with relatively high doses of vitamin D and the anti-inflammatory drug ibuprofen.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/asweetlife.org\/?p=31885\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"ASweetLife Team\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/asweetlife.org\/?p=31885\",\"url\":\"https:\/\/asweetlife.org\/?p=31885\",\"name\":\"Diamyd to Launch New Clinical Study of Diabetes Vaccine in Children\",\"isPartOf\":{\"@id\":\"https:\/\/asweetlife.org\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/asweetlife.org\/?p=31885#primaryimage\"},\"image\":{\"@id\":\"https:\/\/asweetlife.org\/?p=31885#primaryimage\"},\"thumbnailUrl\":\"https:\/\/asweetlife.org\/wp-content\/uploads\/2013\/01\/Diamyd_logo.jpg\",\"datePublished\":\"2013-01-30T10:56:51+00:00\",\"dateModified\":\"2015-12-30T08:02:07+00:00\",\"author\":{\"@id\":\"https:\/\/asweetlife.org\/#\/schema\/person\/5de2b093878b82b0ea97917f8fd72585\"},\"description\":\"The study combines the diabetes vaccine Diamyd with relatively high doses of vitamin D and the anti-inflammatory drug ibuprofen.\",\"breadcrumb\":{\"@id\":\"https:\/\/asweetlife.org\/?p=31885#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/asweetlife.org\/?p=31885\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/asweetlife.org\/?p=31885#primaryimage\",\"url\":\"https:\/\/asweetlife.org\/wp-content\/uploads\/2013\/01\/Diamyd_logo.jpg\",\"contentUrl\":\"https:\/\/asweetlife.org\/wp-content\/uploads\/2013\/01\/Diamyd_logo.jpg\",\"width\":166,\"height\":86,\"caption\":\"Diamyd_logo\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/asweetlife.org\/?p=31885#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/asweetlife.org\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Diamyd to Launch New Clinical Study of Diabetes Vaccine in Children\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/asweetlife.org\/#website\",\"url\":\"https:\/\/asweetlife.org\/\",\"name\":\"ASweetLife\",\"description\":\"The Diabetes Magazine\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/asweetlife.org\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\/\/asweetlife.org\/#\/schema\/person\/5de2b093878b82b0ea97917f8fd72585\",\"name\":\"ASweetLife Team\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/asweetlife.org\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/ba76b5c6c27d32738b13f9a8a5cfcf02?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/ba76b5c6c27d32738b13f9a8a5cfcf02?s=96&d=mm&r=g\",\"caption\":\"ASweetLife Team\"},\"url\":\"https:\/\/asweetlife.org\/?author=131\"}]}<\/script>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"Diamyd to Launch New Clinical Study of Diabetes Vaccine in Children","description":"The study combines the diabetes vaccine Diamyd with relatively high doses of vitamin D and the anti-inflammatory drug ibuprofen.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/asweetlife.org\/?p=31885","twitter_misc":{"Written by":"ASweetLife Team","Est. reading time":"2 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/asweetlife.org\/?p=31885","url":"https:\/\/asweetlife.org\/?p=31885","name":"Diamyd to Launch New Clinical Study of Diabetes Vaccine in Children","isPartOf":{"@id":"https:\/\/asweetlife.org\/#website"},"primaryImageOfPage":{"@id":"https:\/\/asweetlife.org\/?p=31885#primaryimage"},"image":{"@id":"https:\/\/asweetlife.org\/?p=31885#primaryimage"},"thumbnailUrl":"https:\/\/asweetlife.org\/wp-content\/uploads\/2013\/01\/Diamyd_logo.jpg","datePublished":"2013-01-30T10:56:51+00:00","dateModified":"2015-12-30T08:02:07+00:00","author":{"@id":"https:\/\/asweetlife.org\/#\/schema\/person\/5de2b093878b82b0ea97917f8fd72585"},"description":"The study combines the diabetes vaccine Diamyd with relatively high doses of vitamin D and the anti-inflammatory drug ibuprofen.","breadcrumb":{"@id":"https:\/\/asweetlife.org\/?p=31885#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/asweetlife.org\/?p=31885"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/asweetlife.org\/?p=31885#primaryimage","url":"https:\/\/asweetlife.org\/wp-content\/uploads\/2013\/01\/Diamyd_logo.jpg","contentUrl":"https:\/\/asweetlife.org\/wp-content\/uploads\/2013\/01\/Diamyd_logo.jpg","width":166,"height":86,"caption":"Diamyd_logo"},{"@type":"BreadcrumbList","@id":"https:\/\/asweetlife.org\/?p=31885#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/asweetlife.org\/"},{"@type":"ListItem","position":2,"name":"Diamyd to Launch New Clinical Study of Diabetes Vaccine in Children"}]},{"@type":"WebSite","@id":"https:\/\/asweetlife.org\/#website","url":"https:\/\/asweetlife.org\/","name":"ASweetLife","description":"The Diabetes Magazine","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/asweetlife.org\/?s={search_term_string}"},"query-input":"required name=search_term_string"}],"inLanguage":"en-US"},{"@type":"Person","@id":"https:\/\/asweetlife.org\/#\/schema\/person\/5de2b093878b82b0ea97917f8fd72585","name":"ASweetLife Team","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/asweetlife.org\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/ba76b5c6c27d32738b13f9a8a5cfcf02?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/ba76b5c6c27d32738b13f9a8a5cfcf02?s=96&d=mm&r=g","caption":"ASweetLife Team"},"url":"https:\/\/asweetlife.org\/?author=131"}]}},"_links":{"self":[{"href":"https:\/\/asweetlife.org\/index.php?rest_route=\/wp\/v2\/posts\/31885"}],"collection":[{"href":"https:\/\/asweetlife.org\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/asweetlife.org\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/asweetlife.org\/index.php?rest_route=\/wp\/v2\/users\/131"}],"replies":[{"embeddable":true,"href":"https:\/\/asweetlife.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=31885"}],"version-history":[{"count":0,"href":"https:\/\/asweetlife.org\/index.php?rest_route=\/wp\/v2\/posts\/31885\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/asweetlife.org\/index.php?rest_route=\/wp\/v2\/media\/31886"}],"wp:attachment":[{"href":"https:\/\/asweetlife.org\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=31885"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/asweetlife.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=31885"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/asweetlife.org\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=31885"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}