{"id":6990,"date":"2010-04-20T06:23:53","date_gmt":"2010-04-20T10:23:53","guid":{"rendered":"http:\/\/asweetlife.org\/?p=6990"},"modified":"2015-12-29T09:01:19","modified_gmt":"2015-12-29T14:01:19","slug":"diabetes-drug-metformin-may-help-prevent-lung-cancer","status":"publish","type":"post","link":"https:\/\/asweetlife.org\/?p=6990","title":{"rendered":"Diabetes Drug Metformin May Help Prevent Lung Cancer"},"content":{"rendered":"
\n

\"\"<\/a>According to an American Association for Cancer Research (AACR)\u00a0press release, new research presented at the\u00a0AACR 101st Annual Meeting 2010\u00a0suggests the type 2 diabetes drug may soon\u00a0be used in the prevention of lung cancer<\/p>\n

Metformin decreases levels of insulin-like growth factor-1 (IGF-1) and circulating insulin, which is important in patients with type 2 diabetes. However, emerging research suggests metformin may inhibit tumor growth as well.<\/p>\n

For the current study, Dr. Dennis, senior investigator in the medical oncology branch of the National Cancer Institute,\u00a0\u00a0and colleagues treated mice with metformin for 13 weeks following exposure to a nicotine-derived nitrosamine (NNK), which is the most prevalent carcinogen in tobacco and a known promoter of lung tumorigenesis.<\/p>\n

When given orally, metformin was well tolerated and reduced tumor burden by 40 percent to 50 percent. Dennis said levels of metformin reached in mice are readily achievable in humans.<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

According to an American Association for Cancer Research (AACR) press release, new research presented at the AACR 101st Annual Meeting 2010 suggests the type 2 diabetes drug may soon be used in the prevention of lung cancer….<\/p>\n","protected":false},"author":131,"featured_media":29452,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_relevanssi_hide_post":"","_relevanssi_hide_content":"","_relevanssi_pin_for_all":"","_relevanssi_pin_keywords":"","_relevanssi_unpin_keywords":"","_relevanssi_related_keywords":"","_relevanssi_related_include_ids":"","_relevanssi_related_exclude_ids":"","_relevanssi_related_no_append":"","_relevanssi_related_not_related":"","_relevanssi_related_posts":"","_relevanssi_noindex_reason":"","footnotes":""},"categories":[1456,1442],"tags":[142,261],"yoast_head":"\nDiabetes Drug Metformin May Help Prevent Lung Cancer<\/title>\n<meta name=\"description\" content=\"According to an American Association for 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