Category: Science

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Study Reveals New Understanding of Type 1 Diabetes Development

Researchers from the John Curtin School of Medical Research in Canberra, Australia have discovered that the insulin-producing beta cells need a complex sugar, heparan sulfate, for their survival and without it they die. Replacement of heparan sulfate in the beta cells rescues the cells from dying in culture and protects them from oxidative damage...
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Novartis Terminates Study in Type 2 Diabetes Patients

Novartis has decided to terminate the ALTITUDE study evaluating the potential benefits of Rasilez/Tekturna (aliskiren) in reduction of risk of cardiovascular and renal events in patients with type 2 diabetes and renal impairment...
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JDRF to Support Cell Therapy Research for Type 1 Diabetes

JDRF announced it will support a pioneering diabetes research program that is developing a first-of-its-kind cell therapy for type 1 diabetes and other forms of insulin-dependent diabetes. The therapy is a combination product that packages immature cells made from human embryonic stem cells (hESCs) that over time develop into mature pancreatic hormone producing cells...
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Joslin Researchers Help Understand Diabetes in Asian Americans

Researchers at Joslin Diabetes Center have determined key differences between Type 1 and Type 2 diabetes in the Asian American population. This study, published today in PLoS ONE, identified ways to differentiate the types of diabetes, which can be clinically similar in young Asian Americans.
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Diapep277

Positive Results for DiaPep277 Type 1 Diabetes Treatment in Phase 3 Study

Andromeda Biotech has announced positive initial results from a pivotal phase III clinical study of type 1 diabetes treatment, DiaPep227. The 24-month randomized, placebo-controlled study was designed to assess the safety and efficacy of DiaPep277, a novel immunotherapeutic agent for the treatment of newly diagnosed patients with type 1 diabetes...
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JDRF and the Helmsley Charitable Trust to Work Together to Accelerate Diabetes Research

The Juvenile Diabetes Research Foundation (JDRF) and The Leona M. and Harry B. Helmsley Charitable Trust, two of the largest non-government funders of type 1 diabetes programs, announced that they have formalized a collaboration that will foster a new level of cooperation between the organizations. The goal of the collaboration...
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VTT Finland

Researchers Discover Potential Avenues for Early Detection of Type 1 Diabetes

A new study from VTT Technical Research Centre of Finland has found that type 1 diabetes, or autoimmune diabetes, is preceded by diminished gut microbial diversity of the Clostridium leptum subgroup, elevated plasma leptin and enhanced glucose-stimulated insulin secretion. In the past, VTT researches have found that specific metabolic disturbances...
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Creating Glucose-Responsive Insulin: The Crowdsourcing Approach

From its isolation and first use in 1922, insulin has been called one of the few miracle drugs, saving diabetics from the early death of an untreatable disease. Any diabetic nowadays, however, will tell you-- insulin treatment for glucose control is a tricky business.
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