Science | Page 26 of 29

Stem Cell Treatment for Type 1 Diabetes Receives FDA Orphan Drug Designation

Osiris Therapeutics, Inc. announced that it has been granted Orphan Drug designation from the U.S. Food and Drug Administration (FDA) for Prochymal as a treatment for type 1 diabetes mellitus. The FDA instituted the Orphan Drug Act to promote the development of treatments for underserved patient populations...

JDRF Funds Clinical Trial to Test Pig Islet Cells

The Juvenile Diabetes Research Foundation announced today that it is partnering with Living Cell Technologies (LCT), a New Zealand-based biotechnology company focused on developing cell based therapeutics, in a Phase II clinical trial to study the safety and effectiveness of transplanting encapsulated insulin-producing cells from pigs as a treatment for type 1 diabetes with significant hypoglycemia unawareness....

Artificial Pancreas Shows Promise in Israel

An artificial pancreas recently developed at the National Center for Childhood Diabetes at Schneider Children's Hospital in Israel, was tested on seven patients between the ages of 19 and 30. The device consists of a pump that releases insulin and a sensor, which is connected to a small computer which calculates the required amount of insulin to be delivered...

Islet Sheet Technology

The Islet Sheet looks like a clear business card and feels wet and slick on the finger. You can see the islets, which look to the naked eye like fine white sand...

Fat Loss Boosts Immune System in Obese and Type 2 Diabetics

Scientists from the Garvan Institute of Medical Research in Sydney Australia have shown for the first time that even modest weight loss reverses many of the damaging changes often seen in the immune cells of obese people, particularly in those with Type 2 diabetes...

Gene May Tie Stress to Obesity and Diabetes

A research team led by Dr. Alon Chen of the Weizmann Institute’s Neurobiology Department has discovered that changes in the activity of a single gene in the brain not only cause mice to exhibit anxious behavior, but also lead to metabolic changes that cause the mice to develop...

Successful First Trial for Artificial Pancreas

The new artificial pancreas system developed at Boston University was able to maintain near-normal glucose levels without causing hypoglycemia in a small group of type 1 diabetic patients in the first clinical trial conducted at Massachusetts General Hospital....

Researchers Cure Type 1 Diabetes in Mice

Using a sophisticated nanotechnology-based “vaccine,” researchers were able to successfully cure mice with type 1 diabetes and slow the onset of the disease in mice at risk for the disease. The study, co-funded by the Juvenile Diabetes Research Foundation, provides new and important insights into understanding how to stop the immune attack that causes type 1 diabetes...

Sanofi-Aventis and CureMD sign $335M Deal on Diabetes Cure Development

Sanofi-aventis announced that it has signed a global license agreement with CureDM Group on a novel human peptide, Pancreate™, which could restore a patients’ ability to produce insulin and other pancreatic hormones in both type 1 and type 2 diabetes. Pancreate™ is a bioactive peptide sequence of a naturally occurring human protein that has been shown...

The Regeneration of Beta Cells

A new study shows alpha cells in the pancreas, the cells which secrete the hormone glucagon, can regenerate themselves into insulin-producing beta cells...