Researchers from the John Curtin School of Medical Research in Canberra, Australia have discovered that the insulin-producing beta cells need a complex sugar, heparan sulfate, for their survival and without it they die. Replacement of heparan sulfate in the beta cells rescues the cells from dying in culture and protects them from oxidative damage...
Category: Science
Novartis has decided to terminate the ALTITUDE study evaluating the potential benefits of Rasilez/Tekturna (aliskiren) in reduction of risk of cardiovascular and renal events in patients with type 2 diabetes and renal impairment...
JDRF announced it will support a pioneering diabetes research program that is developing a first-of-its-kind cell therapy for type 1 diabetes and other forms of insulin-dependent diabetes. The therapy is a combination product that packages immature cells made from human embryonic stem cells (hESCs) that over time develop into mature pancreatic hormone producing cells...
Researchers at Joslin Diabetes Center have determined key differences between Type 1 and Type 2 diabetes in the Asian American population. This study, published today in PLoS ONE, identified ways to differentiate the types of diabetes, which can be clinically similar in young Asian Americans.
The U.S. Food and Drug Administration (FDA) issued draft guidance designed to help investigators and manufacturers as they develop and seek approval for artificial pancreas device systems to treat type 1 diabetes. This step comes after a large campaign led by the Juvenile Diabetes research Foundation ...
Andromeda Biotech has announced positive initial results from a pivotal phase III clinical study of type 1 diabetes treatment, DiaPep227.
The 24-month randomized, placebo-controlled study was designed to assess the safety and efficacy of DiaPep277, a novel immunotherapeutic agent for the treatment of newly diagnosed patients with type 1 diabetes...
The Juvenile Diabetes Research Foundation (JDRF) and The Leona M. and Harry B. Helmsley Charitable Trust, two of the largest non-government funders of type 1 diabetes programs, announced that they have formalized a collaboration that will foster a new level of cooperation between the organizations. The goal of the collaboration...
While we wait and hope for a diabetes cure, we make the most of the technology that helps us manage our disease...
A new study from VTT Technical Research Centre of Finland has found that type 1 diabetes, or autoimmune diabetes, is preceded by diminished gut microbial diversity of the Clostridium leptum subgroup, elevated plasma leptin and enhanced glucose-stimulated insulin secretion. In the past, VTT researches have found that specific metabolic disturbances...
From its isolation and first use in 1922, insulin has been called one of the few miracle drugs, saving diabetics from the early death of an untreatable disease. Any diabetic nowadays, however, will tell you-- insulin treatment for glucose control is a tricky business.