Researchers have gained an understanding of these presymptomatic stages of type 1 diabetes through the TrialNet data, and through studies including TEDDY (The Environmental Determinants of Diabetes in the Young), which for the past decade has been collecting data from 400,000 children genetically at risk of developing T1D.
Category: Science
For Gina’s second transplant (two years after the failure of the first) researchers at City of Hope added a component of treatment called anti-thymoglobbulin induction, or ATG, which is designed to keep the body’s immune system from harming the new islet cells.
You’ve likely read or heard about your gut bacteria, and how scientists and clinicians are developing a much greater understanding of the effects this additional “other organ” on our health and wellness. It’s truly amazing that there are more bacteria living in our gut than there are cells that make up our body! These bacteria have an enormous impact on the development of our immune systems.
Covalent Data, Inc. announced an agreement that provides JDRF with the ability to track and analyze the resultant output of grant awards to academic researchers. JDRF has helped direct more than $2 billion in research funding since its inception.
We are excited to learn that based on the ten years of clinical trials at UVA, a new startup, Type Zero, is taking the inControl Diabetes Management Platform -- which is the software running the UVA AP -- to the next level.
Philip J. Shaw of the JDCA argues that their analysis of JDRF funding shows that not only has the amount of money being spent on cure research declined, but that the chunk of money spent on research is a shrinking part of the JDRF’s overall budget.
This is an important study because really it’s the first to show a defined effect between the development of the microbiome in infancy and the diagnosis of type 1 diabetes. It opens doors to further questions. What I think will come out of this are targeted, prophylactic treatments rather than something that’s meant to cure disease. Scientists need to dig further into what are the important species that are protective in these children.
The study could have important implications for identifying the disease at a very early stage, delaying its onset or even preventing it altogether. Dr. Julia Greenstein, vice president of discovery research at JDRF, which helped fund the study, says that the work is very preliminary, but points toward strategies for prevention that haven’t yet been explored.
Faustman says that her work has raised the ire of some scientists and organizations for two reasons: It runs counter to the prevailing research emphasis to either prevent type 1 diabetes, or reverse it in people who have been recently diagnosed with diabetes and, at the time, ran into a stiff political headwind from embryonic stem cell researchers.
The Diabetes Research Institute (DRI), a Center of Excellence at the University of Miami Miller School of Medicine, announced today that the first…