Category: Research

Helmsley Charitable Trust

Helmsley Type 1 Diabetes Program Announces $5M Request for Proposals 

The Type 1 Diabetes Program of The Leona M. and Harry B. Helmsley Charitable Trust has announced the launch of the Diabetes Data Innovation Initiative through which it will provide up to $5 million in funding over the next two years. The funding will go to innovative solutions that enable the use of data to ease the burden of type 1 diabetes (T1D) for those living with the disease, their caregivers and healthcare providers.
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Could Reversing Inflammation Cure Diabetes?

Could Reversing Inflammation Cure Diabetes?

Scientists have successfully reversed type 1 diabetes in mice by using adult stem cells and cell surface molecular engineering to reduce the destruction of insulin-producing islet cells. The key to the breakthrough was introducing adult stem cells...
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DIA - Researchers Aim to Stop Type 1 Diabetes Before it Starts

Researchers Aim to Stop Type 1 Diabetes Before it Starts

Researchers with the Janssen Pharmaceutical Companies of Johnson & Johnson recently announced a plan to prevent type 1 diabetes by intercepting the disease in its earliest stages and stopping its development before the onset of symptoms.
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Janssen_logo - JnJ

JDRF and Janssen Team Up to Intercept Type 1 Diabetes

Janssen Research & Development, one of the Janssen Pharmaceutical Companies of Johnson & Johnson, announced that it will invest in a novel scientific approach, called disease interception, to find ways to intercept type 1 diabetes using new diagnostic and pre-disease intervention strategies. If successful, this approach has the potential to transform the standard of care in type 1 diabetes.
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Timothy Kieffer - Lab

Building Beta Cells: An Interview with Dr. Timothy Kieffer

The benefit of making mature beta cells entirely in the dish is that they may be a useful resource for research aimed at understanding the causes of diabetes (both Type 1 and Type 2) as well as developing new therapeutic strategies for diabetes. Moreover, ultimately, mature beta cells may prove to be better than pancreatic progenitor cells for transplant into patients with diabetes.
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ADA-Logo

Asian Americans Develop Diabetes at Lower BMI Levels

The American Diabetes Association (ADA) has decided to lower the Body Mass Index (BMI) cut point at which it recommends screening Asian Americans for type 2 diabetes. This change in ADA guidelines is aligned with evidence that many Asian Americans develop the disease at lower BMI levels than the population at large, according to a position statement being published in the January issue of Diabetes Care.
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Orgenesis - cartoon by Jennefir Jacobs

Orgenesis Receives New Patent for Potential T1D Cure

The liver and pancreas originate from the same embryonic lineage – the endoderm. In fact, both organs develop from the same original group of cells in the embryo. Because of this, they also share many genetic transcription factors and – perhaps most importantly – they each have a built-in glucose sensing system.
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Human stem cell derived beta cells

On the Road to a Type 1 Diabetes Cure: Melton Lab Creates Functioning Beta Cells

Using human embryonic stem cells as a base, the lab has pioneered a process that can reproduce human, insulin-producing beta cells on a large scale. As Melton said in a conference call with journalists, “What we’re reporting on is something that I think was obvious to many as a possible solution but just turned out to be difficult to achieve, and that is the creation of human beta cells that properly respond to sugar or glucose and secrete the right amount of insulin.”
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