Research | Page 9 of 22

JDRF Type 1 Diabetes Research Updates: What You Need to Know

I am a lucky JDRF volunteer. I get to learn all about Type 1 diabetes research, have it translated for me into my own language (which is “regular person who does not know big words”), and then I get to go all over the country sharing news about Type 1 diabetes research with others who speak my language.

Can Treg Infusions Thwart the Immune Response in Type 1 Diabetes?

What researchers are investigating through Rooney’s trial is whether or not another component of the immune system called T regulatory cells, or Tregs, can thwart the aggressive immune response that destroys beta cells, according to Dr. Douglas Losordo, Chief Medical Officer for NeoStem, the company developing and testing the Treg treatment.

Diamyd-Licensed Technology Cures Type 1 Diabetes in Mice

Researchers at UCLA have confirmed earlier findings that combinations of GABA and Antigen Based Therapy (ABT) works synergistically as a treatment in the NOD mouse model of type 1 diabetes. Diamyd Medical is the exclusive licensee for the commercialization of UCLA's GABA technology for metabolic diseases including in diabetes.

Islet Cell Transplant for Type 2 Diabetes: Could it Work?

“I’m a big proponent of islet cell transplantation for type 2 diabetics,” says Dr. Gordon Weir, who is one of the world’s foremost experts on islet cell transplantation as Co-Head of the Section on Islet Cell and Regenerative Biology, the Diabetes Research and Wellness Foundation Chair at the Joslin Diabetes Center, and Professor of Medicine at Harvard Medical School. “I tell people this and they look at me like I’m a little nuts. But, I believe there is no reason it couldn’t work effectively. I’m actually more optimistic about islet cell transplant for type 2 than for type 1.”

LADA and GAD: Diagnosing Type 1.5 Diabetes

Until now, the effectiveness of GAD antibody testing as a diagnostic has not been completely endorsed by the scientific community. Researchers at the Institute of Diabetes Research at the Helmholtz Zentrum München, partners in the Deutsches Zentrum für Diabetesforschung (DZD - German Center for Diabetes Research) however, have concluded a study that recommends use of the test in diagnosing LADA.

Getting Insulin from Gut Cells: Diabetes Cure Research

“If we really want to have an effective therapy for diabetes, we need something that works as well as a beta cell,” Dr. Stanger explains, adding that cell therapy, rather than insulin or drug therapy, “actually gives cells back to people to replace the ones that are no longer working or have been destroyed.”

Smart Insulin: A JDRF Video

In 2003, an MIT chemical engineer founded a company called SmartCells, to develop smart insulin. Smart insulin is a form of insulin that circulates in the bloodstream and turns on when it’s needed to lower blood sugars and off when blood sugars are at safe levels.

Lawrence Steinman’s ‘Reverse Vaccine’ Targets Immune Response in Type 1 Diabetes

Sometimes, when you’re stuck and spinning your wheels without making much forward progress, putting it in reverse can get you going. That’s what Dr. Lawrence Steinman and his colleagues are doing by attempting to cure type 1 diabetes with a unique and groundbreaking “reverse vaccine.”

Learn about JDRF’s Encapsulation Efforts

n efforts to reach the ultimate goal of a world without T1D, JDRF has been a leader in driving encapsulation research forward.

FDA Grants Orphan Drug Status to DiaVacs’s Type 1 Diabetes Reversal Drug

The FDA has granted orphan drug designation for the DiaVacs's type 1 diabetes therapy, DV-0100. The therapy halt’s the body’s autoimmune reaction against the pancreatic islet cells which are responsible for producing insulin, thus allowing them to produce insulin normally and reversing the trajectory of the disease.