The FDA has granted orphan drug designation for the DiaVacs's type 1 diabetes therapy, DV-0100. The therapy halt’s the body’s autoimmune reaction against the pancreatic islet cells which are responsible for producing insulin, thus allowing them to produce insulin normally and reversing the trajectory of the disease.
Category: Cure
Bonner-Weir and other scientists have argued that either the beta cells in the pancreas continue to make copies of themselves, or that the pancreatic ducts, through a process called budding or neurogenesis, continue producing new cells.
The results of the AbATE clinical trial to slow the progression of type 1 diabetes have been trickling out at conferences and talks for a while now,…
Dr. Ferber wants to take a patient’s own liver cells, turn them into beta cells in the lab, and then put them back in the patient just like an islet cell transplant. Because the starting cells are the patient’s own cells, important protein markers on the cells would “match” what the patient’s immune system expects, and the cells would in theory not induce an immune reaction like an organ transplant would.
Dr. Harrison and his team identified that some T cells express a molecule on their surfaces, CD52, that is capable of suppressing other T cells. Understanding the ways in which the immune system normally controls and suppresses T cells is crucial to our understanding what goes wrong in autoimmune diseases.
The biomaterial holding the islet cells—which is completely synthetic, is 96 percent water, and which Garcia described as having the consistency of diluted Jello-O—and that was infused into the mice, however, addresses several of these problems.
Of course, given the opportunity cure type 1 diabetes, to eradicate the condition causing me to take insulin injections twice a day, causing me to black out a few times a year, destroying my fingertips with blood sugar testing, and generally making my life unpleasant and inconvenient on one side of the scale and a living hell on the other, I leapt at it.
Diamyd Medical is planning to launch a new clinical study with its diabetes vaccine, Diamyd, during February 2013.
The study, approved by the Swedish Medical Products Agency, combines the diabetes vaccine Diamyd with relatively high doses of vitamin D and the anti-inflammatory drug ibuprofen. The purpose of the treatment is to preserve the body's own ability to control the blood sugar level in children and adolescents newly diagnosed with type 1 diabetes.
Last week, diabetes headlines were dominated by a new study from the Faustman Lab at Massachusetts General Hospital, published on Wednesday, August 8th on PLoS One, suggesting that a 90-year-old tuberculosis vaccine called BCG might hold promise for people living with type 1 diabetes. “Human Study Reignites Debate Over Controversial Diabetes ‘Cure,’” wrote Reuters. “Diabetes May Be Reversed By Long-Used Vaccine for TB,” proclaimed Bloomberg news.
JDRF-funded researchers at Harvard School of Public Health have found that an experimental drug, called TUDCA, can dramatically reduce the occurrence of type 1 diabetes...