Scientists have successfully reversed type 1 diabetes in mice by using adult stem cells and cell surface molecular engineering to reduce the destruction of insulin-producing islet cells.
The key to the breakthrough was introducing adult stem cells...
Tag: Stem Cell Research
Dr. Doug Melton's group at Harvard, which has made many advances in our understanding of stem cell and beta cell biology over the years, has identified a new hormone, which they called betatrophin, that, when produced by the liver, induces beta cell growth in the islets of the pancreas.
One year after Osiris Therapeutics in partnership with JDRF started the Phase 2 trial evaluating Prochymal, a formulation of adult mesenchymal stem cells (MSCs), in newly diagnosed type 1 diabetes patients, the company has released a statement providing an update on this groundbreaking trial. This first-of-its kind trial is...
Stem cells and diabetes are old friends, and if you’ve spent any time reading about diabetes, you probably have at least a vague sense that…
Human spermatogonial stem cells extracted from testicular tissue can be turned into insulin-secreting beta islet cells normally found in the pancreas, say scientists from Georgetown University Medical Center (GUMC)...
Osiris Therapeutics, Inc. announced that it has been granted Orphan Drug designation from the U.S. Food and Drug Administration (FDA) for Prochymal as a treatment for type 1 diabetes mellitus. The FDA instituted the Orphan Drug Act to promote the development of treatments for underserved patient populations...
Osiris Therapeutics, Inc. today announced that it has achieved a $750,000 milestone payment from the Juvenile Diabetes Research Foundation (JDRF) for completing enrollment in a Phase II clinical trial evaluating Prochymal, an adult mesenchymal stem cell therapy, as a treatment for patients recently diagnosed with type 1 diabetes. The milestone is the fourth in a series of payments resulting from JDRF's partnership with Osiris.
The National Institute of Health (NIH) announced the approval of the first 13 human embryonic stem cell (hESC) lines for use in NIH-funded research under the NIH Guidelines for Human Stem Cell Research adopted in July 2009.
Children's Hospital Boston developed 11 of the approved lines and Rockefeller University in New York City developed two of the approved lines....
I just turned on my computer to work on a different project (see 101 Places Not To See Before You Die) and got an update from JDRF that I needed to share.…
Novocell, a San Diego-based stem cell engineering company, just announced that it’s going to partner up with Japanese researcher Shinya…