Islet Cell Transplantation Right Under the Skin

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Islet Cell Transplantation Right Under the Skin

Dr. James Shapiro, the man who perfected the islet cell transplant to cure type 1 diabetes, is evolving his groundbreaking research by working on a method of implanting insulin-producing cells under a person’s skin to try and stamp out the condition once and for all. Read more

Jordanian Researchers Working on Stem Cell Treatment for Type 1 Diabetes

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Stem Cells

“We have developed a special protocol to purify groups of specific types of stem cells taken from the patient’s own blood, and transplant them into the pancreas to allow for their differentiation into beta cells that produce insulin…” Read more

The Stages of Type 1 Diabetes (It Starts Earlier Than We Thought)

3 Stages of Type 1 Diabetes

Researchers have gained an understanding of these presymptomatic stages of type 1 diabetes through the TrialNet data, and through studies including TEDDY (The Environmental Determinants of Diabetes in the Young), which for the past decade has been collecting data from 400,000 children genetically at risk of developing T1D. Read more

The Most Vital Areas in Diabetes Research Today

Diabetes Research

You’ve likely read or heard about your gut bacteria, and how scientists and clinicians are developing a much greater understanding of the effects this additional “other organ” on our health and wellness. It’s truly amazing that there are more bacteria living in our gut than there are cells that make up our body! These bacteria have an enormous impact on the development of our immune systems. Read more

Type Zero: Taking the Artificial Pancreas to the Next Level

Artificial Pancreas - Type Zero Trial

We are excited to learn that based on the ten years of clinical trials at UVA, a new startup, Type Zero, is taking the inControl Diabetes Management Platform — which is the software running the UVA AP — to the next level. Read more

The Link Between Gut Bacteria and Type 1 Diabetes, part 2

Gut Reaction

This is an important study because really it’s the first to show a defined effect between the development of the microbiome in infancy and the diagnosis of type 1 diabetes. It opens doors to further questions. What I think will come out of this are targeted, prophylactic treatments rather than something that’s meant to cure disease. Scientists need to dig further into what are the important species that are protective in these children. Read more

Gut Reaction: The Link Between Gut Bacteria and Type 1 Diabetes

Gut Reaction: The Link Between Gut Bacteria and Type 1 Diabetes

The study could have important implications for identifying the disease at a very early stage, delaying its onset or even preventing it altogether. Dr. Julia Greenstein, vice president of discovery research at JDRF, which helped fund the study, says that the work is very preliminary, but points toward strategies for prevention that haven’t yet been explored. Read more

Faustman’s Research on BCG Vaccine for Reversal of Type 1 Diabetes Continues

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Dr. Faustman's Lab

Faustman says that her work has raised the ire of some scientists and organizations for two reasons: It runs counter to the prevailing research emphasis to either prevent type 1 diabetes, or reverse it in people who have been recently diagnosed with diabetes and, at the time, ran into a stiff political headwind from embryonic stem cell researchers. Read more

The Novo Nordisk Pipeline: An Interview with CMO Todd Hobbs

Dr. Hobbs

Todd Hobbs, the chief medical officer for North America at Novo Nordisk, knows diabetes from all angles: as a patient; as an endocrinologist (for ten years he ran a clinical practice focused on patients of all ages with diabetes); as an executive at a pharmaceutical company working to develop new treatments (he’s worked at Novo Nordisk since 2004); and as a parent (one of his six sons was diagnosed with type 1 at age five) Read more

Could Reversing Inflammation Cure Diabetes?

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Could Reversing Inflammation Cure Diabetes?

Scientists have successfully reversed type 1 diabetes in mice by using adult stem cells and cell surface molecular engineering to reduce the destruction of insulin-producing islet cells.
The key to the breakthrough was introducing adult stem cells… Read more

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