Category: Diabetes Complications

Pfizer Stops Diabetic Nerve Pain Drug Trials at FDA Request

Pfizer Inc. announced, at the request of the U.S. Food and Drug Administration (FDA), the suspension of the chronic low back pain and painful diabetic peripheral neuropathy studies in the clinical program for the investigational compound tanezumab. Investigation of the compound continues in some areas of high unmet medical need, including cancer pain...
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Hemoglobin A1c Levels Differ in Black and White Persons

A new study published in the Annals of Internal Medicine shows hemoglobin A1c levels differ in black and white persons independent of glucose levels. The study looked at 1581 non-Hispanic black and white persons in the Atlanta area between 18 and 87 years of age who did not have known diabetes...
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Novartis

Novartis’ Ranibizumab More Effective Than Laser Treatment in Treating Vision Loss due to Diabetic Macular Edema

Novartis announced that first results of the RESTORE Phase III study show that ranibizumab is significantly more effective than laser treatment, the current standard of care, at treating visual impairment due to diabetic macular edema (DME), a serious complication of diabetes. The one year results show that 37% of patients treated with ranibizumab 0.5 mg alone, and 43% of those treated with ranibizumab...
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Roche

Roche’s Lucentis Effective for Diabetic Retinopathy

A nationwide, government-sponsored study finds that people with a common form of diabetic retinopathy can benefit from a medication first developed to combat another potentially blinding disease, age-related macular degeneration. According to EurekAlert the study found that treating diabetic macular edema (DME) with Roche's ranibizumab (Lucentis) eye injections...
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JDRF Funded Researchers Test Topical Drug to Treat Diabetic Macular Edema

The Juvenile Diabetes Research Foundation (JDRF) announced that researchers at the Wilmer Eye Institute of Johns Hopkins University School of Medicine in Maryland completed a multicenter human clinical trial treating diabetic macular edema with mecamylamine, a topical drug developed by the biotech company CoMentis, Inc. Funding for the study was provided by JDRF through its Industry Drug Development Partnership program...
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Blood Pressure Drug Reduces Risk Of Cardiovascular Disease and Stroke

According to a press release by the AHA, a new study published in Hypertension: Journal of the American Heart Association has shown that a long-acting ACE inhibitor used to reduce blood pressure significantly decreased the risk for cardiovascular disease, including stroke, in normal weight, overweight and obese patients....
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Mechanism Leading to Diabetic Blindness Identified

Diabetic retinopathy is a common side effect of diabetes and the leading cause of blindness in young adults in the United States. Scientists have long known that high blood sugar levels damage blood vessels in the eye, but they didn't know why or how this happens. Now a Michigan State University scientist has...
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