
These approved therapies and other IL-1 targeting drug candidates are in clinical development to address significant diseases including diabetes, cardiovascular disease, rheumatoid arthritis, gout and other inflammation-mediated diseases as well as some forms of cancer. XOMA is currently conducting two Phase 2 clinical trials of XOMA 052 in patients with type 2 diabetes and a Phase 2 trial in type 1 diabetes.
Three FDA-approved therapies that target the IL-1 pathway clinically validate the role of IL-1 in a number of diseases.